Wheat Bran: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Wheat bran is the outer layers of the wheat grain kernel. It's separated from the inner layers during milling. It's rich in soluble and insoluble fiber.

Wheat bran has laxative effects that can increase stool volume and bowel frequency. It also contains proteins, fats, carbohydrates, minerals, vitamins, and antioxidants.

People use wheat bran for constipation, hemorrhoids, and irritable bowel syndrome (IBS). It is also used for colon cancer, diabetes, high cholesterol, and many other conditions, but there is no good scientific evidence to support most of these uses.

Wheat is considered a major food allergen in the US. Wheat contents, including wheat bran, must be labeled on packaged foods and supplement products.

Uses & Effectiveness

Possibly Effective for

Constipation. Taking wheat bran by mouth seems to help restore normal bowel function in people with mild constipation.
Hemorrhoids. Taking wheat bran by mouth might help reduce the risk of getting hemorrhoids in some people.
A long-term disorder of the large intestine that causes stomach pain (irritable bowel syndrome or IBS). Taking wheat bran by mouth seems to improve bowel function in some people with IBS.

Possibly Ineffective for

Colon cancer, rectal cancer. Taking wheat bran by mouth doesn't seem to reduce the risk for colon or rectal cancer.

There is interest in using wheat bran for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Wheat bran is likely safe when used in doses up to 30 grams daily for up to 3 months. It's usually well-tolerated. Side effects might include gas and stomach discomfort.

Special Precautions and Warnings

When taken by mouth: Wheat bran is likely safe when used in doses up to 30 grams daily for up to 3 months. It's usually well-tolerated. Side effects might include gas and stomach discomfort.

Children: Wheat bran is likely safe when taken by mouth in doses up to 10 grams daily. It has been used safely for up to 2 years.

Pregnancy and breast-feeding: Wheat bran is likely safe when taken by mouth during pregnancy and breast-feeding.

Interactions

We currently have no information for Wheat Bran overview.

Dosing

Wheat bran is a source of dietary fiber. Recommendations for dietary fiber intake vary by age.

As medicine, wheat bran has most often been used by adults in doses of 20-30 grams by mouth daily. Speak with a healthcare provider to find out what dose might be best for a specific condition.

View References

REFERENCES:

Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.

Anon. Consensus statement on cereals, fibre and colorectal and breast cancers. Proceedings of the European Cancer Prevention consensus meeting. Santa Margheritia, Italy, 2-5 October 1997. Eur J Cancer Prev 1998;7:S1-83.

Govers MJ, Gannon NJ, Dunshea FR, et al. Wheat bran affects the site of fermentation of resistant starch and luminal indexes related to colon cancer risk: a study in pigs. Gut 1999;45:840-7.

Zhou JR, Erdman JW Jr. Phytic acid in health and disease. Crit Rev Food Sci Nutr 1995;35:495-508.

Alberts DS, Martinez ME, Roe DJ, et al. Lack of effect of a high-fiber cereal supplement on the recurrence of colorectal adenomas. Phoenix Colon Cancer Prevention Physicians' Network. N Engl J Med 2000;342:1156-62.

Schatzkin A, Lanza E, Corle D, et al. Lack of effect of a low-fat, high-fiber diet on the recurrence of colorectal adenomas. Polyp Prevention Trial Study Group. N Engl J Med 2000;342:1149-55.

Fuchs CS, Giovannucci EL, Colditz GA, et al. Dietary fiber and the risk of colorectal cancer and adenoma in women. N Engl J Med 1999;340:169-76.

Van Horn L. Fiber, lipids, and coronary heart disease. A statement for healthcare professionals from the Nutr Committee, Am Heart Assn. Circulation 1997;95:2701-4.

McRorie J, Kesler J, Bishop L, et al. Effects of wheat bran and Olestra on objective measures of stool and subjective reports of GI symptoms. Am J Gastroenterol 2000;95:1244-52.

Chandalia M, Garg A, Lutjohann D, et al. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med 2000;342:1392-8.

Parisi GC, Zilli M, Miani MP, et al. High-fiber diet supplementation in patients with irritable bowel syndrome (IBS): a multicenter, randomized, open trial comparison between wheat bran diet and partially hydrolyzed guar gum (PHGG). Dig Dis Sci 2002;47:1697-704..

Jenkins DJ, Kendall CW, Augustin LS, et al. Effect of wheat bran on glycemic control and risk factors for cardiovascular disease in type 2 diabetes. Diabetes Care 2002;25:1522-8..

Badiali D, Corazziari E, Habib FI, et al. Effect of wheat bran in treatment of chronic nonorganic constipation. A double-blind controlled trial. Dig Dis Sci 1995;40:349-56..

Griffenberg L, Morris M, Atkinson N, Levenback C. The effect of dietary fiber on bowel function following radical hysterectomy: a randomized trial. Gynecol Oncol 1997;66:417-24..

Anti M, Pignataro G, Armuzzi A, et al. Water supplementation enhances the effect of high-fiber diet on stool frequency and laxative consumption in adult patients with functional constipation. Hepatogastroenterology 1998;45:727-32..

Helton WS; SSAT, AGA, ASGE Consensus Panel. 2001 consensus statement on benign anorectal disease. J Gastrointest Surg 2002;6:302-3.

Jensen SL, Harling H, Tange G, et al. Maintenance bran therapy for prevention of symptoms after rubber band ligation of third-degree haemorrhoids. Acta Chir Scand 1988;154:395-98.

Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients). Washington, DC: National Academy Press, 2002. Available at: https://www.nap.edu/books/0309085373/html/.

Hallfrisch J, Scholfield DJ, Behall KM. Blood pressure reduced by whole grain diet containing barley or whole wheat and brown rice in moderately hypercholesterolemic men. Nutr Res 2003;23:1631-42.

Maffei HV, Vicentini AP. Prospective evaluation of dietary treatment in childhood constipation: high dietary fiber and wheat bran intake are associated with constipation amelioration. J Pediatr Gastroenterol Nutr. 2011 Jan;52(1):55-9. doi: 10.1097/MPG.0b013e3181e2c6e2.

De Paepe K, Verspreet J, Rezaei MN, et al. Modification of wheat bran particle size and tissue composition affects colonisation and metabolism by human faecal microbiota. Food Funct 2019;10(1):379-96. doi: 10.1039/c8fo01272e.

Aoe S, Nakamura F, Fujiwara S. Effect of wheat bran on fecal butyrate-producing bacteria and wheat bran combined with barley on Bacteroides abundance in Japanese healthy adults. Nutrients 2018;10(12)1980. doi: 10.3390/nu10121980.

Tuncil YE, Thakkar RD, Arioglu-Tuncil S, Hamaker BR, Lindemann SR. Fecal microbiota responses to bran particles are specific to cereal type and in vitro digestion methods that mimic upper gastrointestinal tract passage. J Agric Food Chem 2018;66(47):12580-93. doi: 10.1021/acs.jafc.8b03469.

Junejo SA, Zhang L, Yang L, et al. Anti-hyperlipidemic and hepatoprotective properties of wheat bran with different particle sizes. J Sci Food Agric 2019;99(4):1990-6. doi: 10.1002/jsfa.9397.

Lei L, Chen J, Liu Y, Wang L, Zhao G, Chen ZY. Dietary wheat bran oil is equally as effective as rice bran oil in reducing plasma cholesterol. J Agric Food Chem 2018;66(11):2765-74. doi: 10.1021/acs.jafc.7b06093.

Rakvaag E, Fuglsang-Nielsen R, Bach Knudsen KE, Hermansen K, Gregersen S. The combination of whey protein and dietary fiber does not alter low-grade inflammation or adipose tissue gene expression in adults with abdominal obesity. Rev Diabet Stud. 2019;15:83-93.

Stamatikos AD, Davis JE, Shay NF, Ajuwon KM, Deyhim F, Banz WJ. Consuming diet supplemented with either red wheat bran or soy extract changes glucose and insulin levels in female obese zucker rats. Int J Vitam Nutr Res. 2020;90(1-2):23-32.

Hallberg L, Rossander L, Skånberg AB. Phytates and the inhibitory effect of bran on iron absorption in man. Am J Clin Nutr. 1987;45(5):988-96.

Fairweather-Tait SJ. The effect of different levels of wheat bran on iron absorption in rats from bread containing similar amounts of phytate. Br J Nutr. 1982;47(2):243-9.

Balasubramanian R, Johnson EJ, Marlett JA. Effect of wheat bran on bowel function and fecal calcium in older adults. J Am Coll Nutr. 1987;6(3):199-208. doi: 10.1080/07315724.1987.10720182.

Petroski W, Minich DM. Is there such a thing as "anti-nutrients"? A narrative review of perceived problematic plant compounds. Nutrients. 2020;12(10):E2929.

Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-information/food-allergen-labeling-and-consumer-protection-act-2004-falcpa.

Bavarsad N, Mapar MA, Safaezadeh M, Latifi SM. A double-blind, placebo-controlled randomized trial of skin-lightening cream containing lycopene and wheat bran extract on melasma. J Cosmet Dermatol. 2020.

Ishikawa H, Akedo I, Otani T, et al. Randomized trial of dietary fiber and Lactobacillus casei administration for prevention of colorectal tumors. Int J Cancer 2005;116(5):762-7.

Lai H, Li Y, He Y, et al. Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial. Gut Microbes 2023;15(1):2197837.

Yan T, Shi L, Liu T, et al. Diet-rich in wheat bran modulates tryptophan metabolism and AhR/IL-22 signalling mediated metabolic health and gut dysbacteriosis: A novel prebiotic-like activity of wheat bran. Food Res Int 2023;163:112179.

Meiller L, Sauvinet V, Breyton AE, et al. Metabolic signature of (13)C-labeled wheat bran consumption related to gut fermentation in humans: a pilot study. Eur J Nutr 2023;62(6):2633-2648.

Martinez TM, Wachsmuth HR, Meyer RK, et al. Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats. Nutr Metab (Lond) 2023;20(1):44.

Abd Elmoneim Elmadbouly M. Effect of Wheat Bran on Anthropometric Measures, Serum Glucose and Lipid Profile in Type 2 Diabetes Patients. Pak J Biol Sci 2021;24(3):345-349.

Deroover L, Vázquez-Castellanos JF, Vandermeulen G, et al. Wheat bran with reduced particle size increases serum SCFAs in obese subjects without improving health parameters compared with a maltodextrin placebo. Am J Clin Nutr 2021;114(4):1328-1341.

Dalile B, La Torre D, Kalc P, et al. Extruded Wheat Bran Consumption Increases Serum Short-Chain Fatty Acids but Does Not Modulate Psychobiological Functions in Healthy Men: A Randomized, Placebo-Controlled Trial. Front Nutr 2022;9:896154.

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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