Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
Goldwaser I, Li J, Gershonov E, et al. L-Glutamic acid gamma-monohydroxamate. A potentiator of vanadium-evoked glucose metabolism in vitro and in vivo. J Biol Chem 1999;274:26617-24.
Aharon Y, Mevorach M, Shamoon H. Vanadyl sulfate does not enhance insulin action in patients with type 1 diabetes. Diabetes Care 1998;21:2194-5.
Klaassen CD, ed. Casarett and Doull's Toxicology: The Basic Science of Poisons. fifth ed. New York: McGraw-Hill, 1996.
Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4.
Malabu UH, Dryden S, McCarthy HD, et al. Effects of chronic vanadate administration in the STZ-induced diabetic rat. Diabetes 1994;43:9-15.
Bishayee A, Karmakar R, Mandal A, et al. Vanadium mediated chemoprotection against chemical hepatocarcinogenesis in rats: haematological and histological characteristics. Eur J Cancer Prev 1997;6:58-70.
Chakraborty A, Chatterjee M. Enhanced erythropoietin and suppression of gamma-glutamyl-transpeptidase (GGT) activity in murine lymphoma following administration of vanadium. Neoplasma 1994;41:291-6.
Domingo JL, Sanchez DJ, Gomez M, et al. Oral vanadate and Tiron in treatment of diabetes mellitus in rats: improvement of glucose homeostasis and negative side effects. Vet Human Toxicol 1993;35:495-500.
Oster MH, Llobet JM, Domingo JL, et al. Vanadium treatment of diabetic Sprague-Dawley rats results in tissue vanadium accumulation and pro-oxidant effects. Toxicology 1993;83:115-30.
Stern A, Yin X, Tsang SS, et al. Vanadium as a modulator of cellular regulatory cascades and oncogene expression. Biochem Cell Biol 1993;71:103-12.
Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
Domingo JL, Gomez M, Llobet JM, et al. Oral vanadium administration to streptozocin-diabetic rats has marked negative side-effects which are independent of the form of vanadium used. Toxicology 1991;66:279-87.
Leonard A, Gerber GB. Mutagenicity, carcinogenicity and teratogenicity of vanadium Compounds. Mutat Res 1994;317:81-8.
Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6.
Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66.
Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501-9.
Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1996;45:1130-5.
Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002. Available at: www.nap.edu/books/0309072794/html/.
Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 2003;26:1277-94.
Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20.
Cusi K, Cukier S, DeFronzo RA, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410-7.
Kelly, G. S. Insulin resistance: lifestyle and nutritional interventions. Altern.Med Rev 2000;5(2):109-132.
Nahas, R. and Moher, M. Complementary and alternative medicine for the treatment of type 2 diabetes. Can Fam.Physician 2009;55(6):591-596.
Badmaev, V., Prakash, S., and Majeed, M. Vanadium: a review of its potential role in the fight against diabetes. J Altern Complement Med 1999;5(3):273-291.
Goldfine, A. B., Patti, M. E., Zuberi, L., Goldstein, B. J., LeBlanc, R., Landaker, E. J., Jiang, Z. Y., Willsky, G. R., and Kahn, C. R. Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies. Metabolism 2000;49(3):400-410.
Beliaeva, N. F., Gorodetskii, V. K., Tochilkin, A. I., Golubev, M. A., Semenova, N. V., and Kovel'man, I. R. [Vanadium compounds--a new class of therapeutic agents for the treatment of diabetes mellitus]. Vopr.Med Khim. 2000;46(4):344-360.
Sakurai, H., Yasui, H., and Adachi, Y. The therapeutic potential of insulin-mimetic vanadium complexes. Expert.Opin Investig.Drugs 2003;12(7):1189-1203.
Henquin, J. C. and Brichard, S. M. [Role of vanadium in the treatment of diabetes mellitus. Experimental data and clinical applications]. Presse Med 6-27-1992;21(24):1100-1101.
Scior, T., Guevara-Garcia, A., Bernard, P., Do, Q. T., Domeyer, D., and Laufer, S. Are vanadium compounds drugable? Structures and effects of antidiabetic vanadium compounds: a critical review. Mini.Rev Med Chem 2005;5(11):995-1008.
Tubek, S. Role of trace elements in primary arterial hypertension: is mineral water style or prophylaxis? Biol.Trace Elem.Res 2006;114(1-3):1-5.
Bradley, R., Oberg, E. B., Calabrese, C., and Standish, L. J. Algorithm for complementary and alternative medicine practice and research in type 2 diabetes. J Altern.Complement Med. 2007;13(1):159-175.
Chakraborty, T., Chatterjee, A., Rana, A., Rana, B., Palanisamy, A., Madhappan, R., and Chatterjee, M. Suppression of early stages of neoplastic transformation in a two-stage chemical hepatocarcinogenesis model: supplementation of vanadium, a dietary micronutrient, limits cell proliferation and inhibits the formations of 8-hydroxy-2'-deoxyguanosines and DNA strand-breaks in the liver of sprague-dawley rats. Nutr Cancer 2007;59(2):228-247.
Smith, D. M., Pickering, R. M., and Lewith, G. T. A systematic review of vanadium oral supplements for glycaemic control in type 2 diabetes mellitus. QJM. 2008;101(5):351-358.
Darvesh, A. S. and Bishayee, A. Selenium in the prevention and treatment of hepatocellular carcinoma. Anticancer Agents Med Chem 2010;10(4):338-345.
Min, J. A., Lee, K., and Ki, D. J. The application of minerals in managing alcohol hangover: a preliminary review. Curr Drug Abuse Rev 2010;3(2):110-115.
Sakurai, H., Katoh, A., Kiss, T., Jakusch, T., and Hattori, M. Metallo-allixinate complexes with anti-diabetic and anti-metabolic syndrome activities. Metallomics. 10-1-2010;2(10):670-682.
Hosokawa, S. and Yoshida, O. Vanadium in chronic hemodialysis patients. Int J Artif.Organs 1990;13(4):197-199.
Mancinella, A. [Vanadium, an indispensable trace element in living organisms. Current data on biochemical, metabolic levels and therapeutic doses]. Clin Ter. 1993;142(3):251-255.
Scheen, A. J. Drug treatment of non-insulin-dependent diabetes mellitus in the 1990s. Achievements and future developments. Drugs 1997;54(3):355-368.
Shi, S. J., Preuss, H. G., Abernethy, D. R., Li, X., Jarrell, S. T., and Andrawis, N. S. Elevated blood pressure in spontaneously hypertensive rats consuming a high sucrose diet is associated with elevated angiotensin II and is reversed by vanadium. J Hypertens. 1997;15(8):857-862.
Cunningham, J. J. Micronutrients as nutriceutical interventions in diabetes mellitus. J Am Coll.Nutr 1998;17(1):7-10.
Neyrolles, N., Blickle, J. F., and Brogard, J. M. [New therapies in type 2 diabetes]. Ann Endocrinol.(Paris) 1998;59(2):67-77.
Shamberger, R. J. The insulin-like effects of vanadium. J Adv Med 1996;(9):121-131.
Jacques-Camarena O, et al. Effect of vanadium on insulin sensitivity in patients with impaired glucose tolerance. Ann Nutr Metab. 2008;53(3-4):195-198.
Gruzewska K, Michno A, Pawelczyk T, Bielarczyk H. Essentiality and toxicity of vanadium supplements in health and pathology. J Physiol Pharmacol. 2014;65(5):603-611.
Peat F, Coomber R, Rana A, Vince A. Vanadium allergy following total knee arthroplasty. BMJ Case Rep 2018;2018. pii: bcr-2017-222092. doi: 10.1136/bcr-2017-222092.
Jin S, Xia W, Jiang Y, et al. Urinary vanadium concentration in relation to premature rupture of membranes: A birth cohort study. Chemosphere 2018;210:1035-41. doi: 10.1016/j.chemosphere.2018.07.110.
Garcia-Nunez I, Algaba-Marmol MA, Suarez-Vergara M, et al. Vanadium contact dermatitis: case report and studies performed. Contact Dermatitis 2019;80(2):127-8.
Zhou Y, Zhu Q, Ma W, et al. Prenatal vanadium exposure, cytokine expression, and fetal growth: a gender-specific analysis in Shanghai MCPC study. Sci Total Environ 2019;685:1152-9.
Jiang S, Zhou S, Liu H, et al. Concentrations of vanadium in urine with hypertension prevalence and blood pressure levels. Ecotoxicol Environ Saf 2021;213:112028.
Zhang W, Chen H, Zeng Q, Xu S, Xia W, Li Y. Prenatal and postnatal exposure to vanadium and the immune function of children. J Trace Elem Med Biol 2021;67:126787.
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