Jambolan: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Jambolan is a tree. The seed, leaf, bark, and fruit are used to make medicine.

Jambolan is widely used in folk medicine for diabetes.

Jambolan seed and bark contains chemicals that might lower blood sugar, but extracts from jambolan leaf and fruit don't seem to affect blood sugar. Jambolan also contains chemicals that might protect against oxidation damage, as well as chemicals that reduce swelling.

It is also used by mouth for gas (flatulence), swelling (inflammation) of the stomach (gastritis), constipation, diarrhea, and other conditions.

Jambolan is sometimes used for sore throat, and applied directly to the skin for skin ulcers.

How does it work ?

Jambolan seed and bark contains chemicals that might lower blood sugar, but extracts from jambolan leaf and fruit don't seem to affect blood sugar. Jambolan also contains chemicals that might protect against oxidation damage, as well as chemicals that reduce swelling.

Uses & Effectiveness

We currently have no information for Jambolan overview.

Side Effects

When taken by mouth: Jambolan is POSSIBLY SAFE for most people when taken by mouth, short-term. Jambolan tea prepared from 2 grams of jambolan leaves per liter of water seems to be safe.

Special Precautions and Warnings

When taken by mouth: Jambolan is POSSIBLY SAFE for most people when taken by mouth, short-term. Jambolan tea prepared from 2 grams of jambolan leaves per liter of water seems to be safe.

Pregnancy and breast-feeding: There isn't enough reliable information to know if jambolan is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Diabetes: Jambolan seed and bark extracts might lower blood sugar levels. Monitor blood sugar levels closely if you have diabetes and take jambolan.

Surgery: Jambolan might lower blood sugar levels. There is some concern that it might interfere with blood sugar control during and after surgery. Stop using jambolan at least 2 weeks before a scheduled surgery.

Interactions

Moderate Interaction

Be cautious with this combination

Medications for diabetes (Antidiabetes drugs) interacts with Jambolan
Jambolan seed and bark extracts might decrease blood sugar levels. Diabetes medications are also used to lower blood sugar. Taking jambolan seed or bark along with diabetes medications might cause your blood sugar to be too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with Jambolan
Some medications are changed and broken down by the liver. Jambolan might decrease how quickly the liver breaks down some medications. Taking jambolan along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before taking jambolan, talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include amitriptyline (Elavil), diazepam (Valium), zileuton (Zyflo), celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin), irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), warfarin (Coumadin), and others.

Minor Interaction

Be watchful with this combination

Sitagliptin (Januvia) interacts with Jambolan
Jambolan seed extract might lower blood levels of the medication sitagliptin. Sitagliptin helps the body lower blood sugar to normal levels in patients with diabetes. Taking jambolan seed along with sitagliptin might cause changes in your blood sugar. Monitor your blood sugar closely. The dose of sitagliptin might need to be changed.

Dosing

The appropriate dose of jambolan depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for jambolan. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

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