Rice Bran Arabinoxylan Compound: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Rice bran arabinoxylan compound is an extract of arabinoxylan from rice bran. It is used as a medicine.

Rice bran arabinoxylan compound is most commonly used for boosting the immune system. It is also used for cancer, reducing side effects of cancer treatment, chronic fatigue syndrome (CFS), hepatitis C, and other conditions, but there is no good scientific evidence to support these uses.

Rice bran arabinoxylan compound might work by improving the body's natural immune system.

How does it work ?

Rice bran arabinoxylan compound might work by improving the body's natural immune system.

Uses & Effectiveness

Insufficient Evidence for

Chronic fatigue syndrome (CFS). Early research suggested that rice bran arabinoxylan compound might improve symptoms and immune function in people with CFS. But more recent evidence shows that rice bran arabinoxylan compound does not improve symptoms of CFS including fatigue. All of the studies to date have been small and/or low quality, so more high quality research is needed.
Swelling (inflammation) of the liver caused by the hepatitis C virus (hepatitis C). Early research suggests that taking rice bran arabinoxylan compound helps to clear hepatitis C virus from the bloodstream in people with a certain type of hepatitis C. It seems to work as well as pegylated interferon plus ribavirin.
HIV/AIDS. Early research shows that taking rice bran arabinoxylan does not improve most blood markers of HIV/AIDS.
Liver cancer. Early research shows that taking rice bran arabinoxylan compound in combination with standard therapy might help people with liver cancer live longer compared to standard therapy alone. It might also help prevent liver cancer from returning after treatment.
Quality of life. Early research shows that taking rice bran arabinoxylan 250 mg daily for 3 months may improve self-reported quality of life in older adults.
Boosting immune function.
Diabetes.
Preventing and treating cancer.
Other conditions.

More evidence is needed to rate the effectiveness of rice bran arabinoxylan compound for these uses.

Side Effects

When taken by mouth: Rice bran arabinoxylan compound is POSSIBLY SAFE when taken by mouth short-term. Rice bran arabinoxylan compound has been used safely in doses of 1 gram daily for 12 months or up to 6 grams daily for 2-3 months. There isn't enough reliable information to know whether rice bran arabinoxylan compound is safe to take for a longer period of time.

Special Precautions and Warnings

Pregnancy and breast-feeding: Not enough is known about the use of rice bran arabinoxylan compound during pregnancy and breast-feeding. Stay on the safe side and avoid use.

"Auto-immune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Rice bran arabinoxylan compound might cause the immune system to become more active. This might increase the symptoms of auto-immune diseases. If you have one of these conditions, it's best to avoid using rice bran arabinoxylan compound.

Interactions

Moderate Interaction

Be cautious with this combination

Medications that decrease the immune system (Immunosuppressants) interacts with Rice Bran Arabinoxylan Compound
Rice bran arabinoxylan compound might increase the immune system. By increasing the immune system, rice bran arabinoxylan compound might decrease the effectiveness of medications that decrease the immune system.
Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.

Dosing

The appropriate dose of rice bran arabinoxylan compound depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for rice bran arabinoxylan compound. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

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Ghoneum M, Jewett A. Synergistic effect of modified arabinoxylane (MGN-3) and low dose of recombinant IL-2 on human NK cell activity and TNF-a production. American Academy of Anti-Aging Medicine, Education Conference 1998.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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