Overview

Japanese persimmon is a tree. People eat the fruit. The fruit and leaf are used for medicine.

Japanese persimmon is used for high blood pressure, fluid retention, constipation, and other conditions, but there is no good scientific evidence to support many of these uses.

Japanese persimmon contains chemicals that might lower blood pressure. There isn't enough information to know how Japanese persimmon works for other conditions.

How does it work ?

Japanese persimmon contains chemicals that might lower blood pressure. There isn't enough information to know how Japanese persimmon works for other conditions.

Uses & Effectiveness

Insufficient Evidence for

  • High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Early research shows that eating fiber from unripe Japanese persimmon fruit may lower lipid levels in the blood.
  • Prediabetes. Early research in people with prediabetes shows that taking Japanese persimmon leaf extract might lower blood sugar.
  • Constipation.
  • Fluid retention.
  • Hiccough.
  • High blood pressure.
  • Improving blood flow.
  • Reducing body temperature.
  • Stroke.
  • Other conditions.

More evidence is needed to rate Japanese persimmon for these uses.

Side Effects

When taken by mouth: Japanese persimmon is POSSIBLY SAFE when taken as a medicine. It has been used in clinical research without reported adverse effects. The fruit might cause allergic reactions in some people, but this is uncommon. Eating the fruit in very large amounts might cause blockage of the intestines.

Special Precautions and Warnings

When taken by mouth: Japanese persimmon is POSSIBLY SAFE when taken as a medicine. It has been used in clinical research without reported adverse effects. The fruit might cause allergic reactions in some people, but this is uncommon. Eating the fruit in very large amounts might cause blockage of the intestines.

Pregnancy and breast-feeding: Not enough is known about the use of Japanese persimmon during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: Taking Japanese persimmon might slow blood clotting. This might increase the risk of bruising and bleeding in people with bleeding disorders.

Low blood pressure: Japanese persimmon might lower blood pressure. There is some concern that it might make low blood pressure worse or interfere with treatment intended to raise low blood pressure.

Surgery: Japanese persimmon might lower blood pressure or slow blood clotting. This might interfere with blood pressure control or increase the chance of excessive bleeding during and after surgery. Stop using Japanese persimmon at least 2 weeks before a scheduled surgery.

Interactions

    Moderate Interaction

    Be cautious with this combination

  • Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with Japanese Persimmon

    Japanese persimmon might slow blood clotting. Taking Japanese persimmon along with medications that also slow clotting might increase the chances of bruising and bleeding.

    Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others.

  • Medications for high blood pressure (Antihypertensive drugs) interacts with Japanese Persimmon

    Japanese persimmon seems to decrease blood pressure. Taking Japanese persimmon along with medications for high blood pressure might cause your blood pressure to go too low.

    Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Dosing

The appropriate dose of Japanese persimmon depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Japanese persimmon. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
View References
Show More Show Less

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is licensed from Therapeutic Research Center, LLC. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
Licensed from Therapeutic Research Center, LLC
Copyright © 1995-2025 by Therapeutic Research Center, LLC. All Rights Reserved.