Medically Reviewed by Poonam Sachdev on August 24, 2025
Understanding GLP-1 Medications
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Understanding GLP-1 Medications

GLP-1 receptor agonists like Ozempic, Mounjaro, and Wegovy are changing weight loss treatment. They mimic hormones that reduce appetite and keep you feeling full but come with potential side effects.

Nausea and Digestive Issues
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Nausea and Digestive Issues

Nausea, vomiting, and diarrhea are common side effects, especially when starting treatment. These symptoms often improve over time as your body adjusts to the medication.

Taste Changes and Food Aversions
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Taste Changes and Food Aversions

Many people report that their sense of taste chances, or they no longer enjoy favorite foods. Sweet and fatty foods may become particularly unappetizing while on GLP-1 medications.

Injection Site Reactions
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Injection Site Reactions

Some patients experience redness, itching, or swelling at injection sites. Injecting yourself in different spots each time and using the right technique can help minimize these reactions.

Pancreas Problems
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Pancreas Problems

In rare cases, GLP-1 medications may cause pancreatitis, or an inflamed pancreas. Seek immediate medical help if you have severe abdominal pain that radiates to your back.

Muscle Loss
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Muscle Loss

You can lose both fat and muscle while on these medications. Make sure you're getting enough protein and do regular strength training to preserve muscle mass.

Gallbladder Complications
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Gallbladder Complications

Rapid weight loss increases the risk of gallstones or an inflamed gallbladder. Let your doctor know about any upper abdominal pain.

Hair Thinning
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Hair Thinning

Some people experience temporary hair thinning due to hormonal changes and reduced nutrient intake. Make sure you're getting enough protein and vitamins.

Mood Changes
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Mood Changes

Some people have mood changes, including depression and anxiety, while on GLP-1s. Let your healthcare provider know about changes in your mental wellbeing.

Thyroid Concerns
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Thyroid Concerns

Animal studies showed an increased risk of thyroid tumors with some GLP-1 medications, but it's not yet known if it can cause thyroid cancer in people.

When to Seek Help
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When to Seek Help

Get medical help immediately for severe abdominal pain, persistent vomiting, or signs of allergic reaction. Tell your doctor if side effects significantly impact your quality of life.

This content was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.