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Overview: Tonmya is a medicine for fibromyalgia. Common side effects include drowsiness and tiredness. Do not drive or operate heavy machinery until you know how Tonmya affects you. Tell your health care provider about all medicines you take before using Tonmya. Get emergency help if you get chest pain, trouble breathing, sudden and severe headache, or see or hear unusual things. Also, get emergency help if you become sweaty, agitated, dizzy, stiff, or confused.

Uses

What is Tonmya used for?

Tonmya (cyclobenzaprine) is commonly used to treat fibromyalgia.

Learn more about Tonmya for fibromyalgia.

Tonmya may also be used for other conditions as determined by your health care provider.

See also: Cyclobenzaprine

How does Tonmya work (mechanism of action)?

Tonmya may help people with pain and sleep problems due to fibromyalgia by affecting neurotransmitters.

How is Tonmya supplied (dosage forms)?

Tonmya is available as a 2.8 mg sublingual tablet that dissolves under the tongue.

How should I store Tonmya?

Tonmya should be stored at room temperature, between 68 F and 77 F (20 C and 25 C). It can be exposed to temperatures between 59 F and 86 F (15 C and 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place. 

Keep Tonmya in its original container, with the bottle tightly closed, to protect it from moisture. Do not remove the desiccant.

Side Effects

What are the most common side effects of Tonmya?

The most common side effects of Tonmya are listed below. Tell your health care provider if you have any of these side effects that bother you.

  • Mouth problems (see below) 
  • Drowsiness
  • Tiredness
  • Dry mouth
  • Unusual taste

There may be other side effects of Tonmya that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Tonmya?

While less common, the most serious side effects of Tonmya are described below, along with what to do if they happen.

Severe Allergic Reactions. Tonmya may cause allergic reactions, which can be serious. Stop using Tonmya and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching or skin rash
  • Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Serotonin Syndrome. Serotonin syndrome is when there is too much of a substance called serotonin in your body. Tonmya can increase the risk of serotonin syndrome when it is used alone or with other medicines that affect serotonin. This condition can be life-threatening. Get emergency help if you have any of the following symptoms of serotonin syndrome.

  • Sweating, fever, or flushing
  • Confusion
  • Feeling agitated or restless
  • Seeing or hearing unusual things
  • Dizziness
  • Fast or racing heartbeat
  • Nausea, vomiting, or diarrhea
  • Muscle twitching, stiffness, or tremor
  • Seizures

Central Nervous System (CNS) Depression. Tonmya may slow down your central nervous system (CNS), which controls many vital functions throughout the body. Call your health care provider right away if you have any of the following symptoms of CNS depression.

  • Confusion
  • Excessive sleepiness or trouble staying awake
  • Memory problems
  • Slow or shallow breathing
  • Slowed response or reaction time
  • Slurred speech

Mouth Problems. Tonmya commonly causes mouth discomfort, pain, numbness, swelling, ulcers, or tingling. Sometimes, these problems can be severe. Tell your health care provider right away if you have any of the following symptoms. 

  • Trouble swallowing, eating, or drinking
  • Mouth pain that causes problems doing your normal activities like brushing your teeth
  • Discomfort, pain, numbness, ulcers, or tingling that affects a large area of your mouth

Heart Attack and Stroke. Tonmya can cause side effects that may increase your risk of a heart attack or stroke. This medicine is not to be used by certain people. See the Warnings and Precautions section for more information. Get emergency help if you have any of the following symptoms of a heart attack or stroke.

  • Chest pain or pressure
  • Fast or abnormal heartbeat
  • Trouble breathing
  • Pain in your back, jaw, throat, or arm
  • Sweating, upset stomach, vomiting, or dizziness
  • Sudden weakness on one side of your body
  • Sudden and severe headache
  • Slurred speech or trouble understanding speech

Warnings & Precautions

Who should not use Tonmya?

Allergies to Ingredients. People who are allergic to any of the following should not use Tonmya.

  • Cyclobenzaprine
  • Tonmya
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Tonmya.

Drug Interactions. Tonmya should not be used while you are using certain other medicines. Before using Tonmya, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Hyperthyroidism. Tonmya should not be used by people with an overactive thyroid. 

Heart Problems. Tonmya should not be used by people with any of the following heart problems.

What should I know about Tonmya before using it?

Do not use Tonmya unless it has been prescribed to you by a health care provider. Use it as prescribed.

Do not share Tonmya with other people, even if they have the same condition as you. It may harm them.

Keep Tonmya out of the reach of children.

Drowsiness and tiredness are common side effects of Tonmya and can affect your alertness or coordination. This medicine is usually taken at night. Try to take this medicine at the same time each night after you brush and floss your teeth. Consider using this medicine right before bedtime if you go to sleep about the same time each night. Do not drive or do other activities that require alertness or coordination until you know how Tonmya affects you.

Do not swallow, cut, crush, or chew Tonmya. 

Take a few sips of water before using Tonmya. Having a moist mouth may lower the risk of having a numb or tingling feeling in your mouth. If you do have mouth symptoms, they usually go away within an hour of using Tonmya. Tell your health care provider right away if you get any mouth symptoms that are severe. 

After you use Tonmya, do not talk for at least 5 minutes. If you have any questions about how to use this medicine, talk with your health care provider. 

If you suddenly stop Tonmya, you may get a headache, nausea, or a general feeling of being unwell, tired, or not having your usual energy. These symptoms are because of how this medicine works in your body. Talk with your health care provider if you want to stop Tonmya.

What should I tell my health care provider before using Tonmya?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Tonmya is right for you.

In particular, make sure that you discuss any of the following.

Other Current and Past Health Conditions. Tell your health care provider if you have any of the following.

  • Seizures
  • Trouble emptying your bladder (problems starting to pee, only peeing small amounts at a time, feeling like your bladder is still full)
  • Benign prostatic hypertrophy
  • Glaucoma
  • Liver problems

Pregnancy. Tonmya may harm an unborn baby. Your health care provider will likely do a test to make sure you are not pregnant before starting Tonmya. Tell your health care provider if you recently could have become pregnant. You may be pregnant, but a test may not turn positive. If you can get pregnant, you should use effective birth control while using Tonmya and for 2 weeks after your last dose. Tell your health care provider right away if you are pregnant, think you may be pregnant, or plan to become pregnant. If you do become pregnant while using Tonmya, you are encouraged to let the drugmaker know by calling 888-869-7633.

Breastfeeding. It is not known if Tonmya passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will let you know if you should use Tonmya while breastfeeding.

How can I get more information about Tonmya?

For more information about Tonmya, you can visit the drugmaker’s website at www.tonmya.com or you can call them at 888-869-7633.

Interactions

Does Tonmya interact with foods or drinks?

Do not eat or drink anything for at least 15 minutes after Tonmya completely dissolves under your tongue. After 15 minutes have passed, do not drink anything that is hot, cold, or acidic until the next morning.

Do not drink alcohol while using Tonmya. The combination can increase sleepiness or affect your alertness or concentration. 

Does Tonmya interact with other medicines (drug interactions)?

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before using Tonmya.

  • A monoamine oxidase inhibitor (MAOI) within the past two weeks, which is a medicine usually used for depression or Parkinson’s disease
  • A tricyclic antidepressant, such as amitriptyline or nortriptyline, even if it is not used for depression
  • A selective serotonin reuptake inhibitor (SSRI) or a serotonin norepinephrine reuptake inhibitor (SNRI), which are medicines commonly used for anxiety and depression
  • Bupropion (Wellbutrin SR, Wellbutrin XL, Aplenzin, and others), which is a medicine used to treat depression or to help quit smoking
  • Verapamil (Verelan, Verelan PM), which is a medicine used for high blood pressure or other conditions
  • An anticholinergic medicine, which includes antihistamines and medicines commonly used for overactive bladder, Parkinson’s disease, or stomach problems
  • A barbiturate, such as butalbital, phenobarbital, or primidone, which is a medicine that may be used to treat insomnia, migraines, or seizures
  • An opioid, such as codeine, fentanyl, morphine, meperidine, tramadol, or oxycodone, which is a medicine used to treat certain types of pain

This may not be a complete list of medicines that can interact with Tonmya. Always check with your health care provider.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Tonmya?

If you or someone else has used too much Tonmya, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Tonmya?

If you miss a dose, skip it. Only use the next dose at your regular time the next night. Do not use double or extra doses.