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BiomePro is available over the counter as a supplement. It contains multiple probiotic bacteria that are naturally found in the gut. BiomePro is used for various reasons, but its benefits are not well defined. Common side effects include gas and upset stomach. Serious side effects are rare but may include infections in some people who are at high risk for infections. Before taking BiomePro, make sure to tell your health care provider about any health conditions you have or the medicines you are taking.

Uses

What is BiomePro used for?

BiomePro is commonly used to improve gut and respiratory health and to strengthen the immune system. However, its benefits are not well defined. 

BiomePro may also be used for other conditions as determined by your health care provider.

Note: The Food and Drug Administration (FDA) has not reviewed BiomePro for safety and effectiveness, and it is not approved by the FDA. Learn more about dietary supplements here.

How does BiomePro work (mechanism of action)?

BiomePro contains multiple species of bacteria, such as Lactobacillus acidophilus (L. acidophilus), L. rhamnosus, L. plantarum, L. paracasei, and Bifidobacterium lactis (B. lactis). Each of these species are probiotics, which means that they are live microbes that may provide health benefits in some people.

There are many different strains within each species of bacteria. BiomePro may contain multiple strains of certain bacteria. For example, L. rhamnosus is a species of bacteria. BiomePro may contain more than one strain of L. rhamnosus. These strains are listed on the product label as the string of numbers or letters that come after the species name, such as “L. rhamnosus HN001.” Each strain of bacteria may have effects on the body that other strains do not.

Your gut is home to millions of different microbes, which make up your gut microbiome. All of the species of bacteria in BiomePro are naturally found in your gut. These bacteria make substances called lactic acid and short-chain fatty acids. Each of these substances can help improve the health of your microbiome by reducing the amount of bad bacteria and increasing the amount of good bacteria. When your gut microbiome is healthy, it can improve your ability to digest foods and resist infections.

Taking BiomePro may increase the levels of these species and strains in your gut. This may help improve the health of your microbiome. But there are many different factors that can affect whether a probiotic survives in your body. When you take BiomePro by mouth, the bacteria may not always survive long enough to grow and multiply in your gut. As a result, its benefits are not well defined and may be different for each person. It is also not clear whether BiomePro can help treat or prevent any health problems.

How is BiomePro supplied (dosage forms)?

BiomePro is a probiotic dietary supplement that is available as a capsule that is swallowed.

How should I store BiomePro?

Storage requirements for BiomePro have not been provided with the product packaging. Most dietary supplements should be kept in a cool, dry location that is out of the reach of children and pets and not in direct sunlight. Ask your pharmacist or other health care provider if you are not sure how to store BiomePro.

Side Effects

What are the most common side effects of BiomePro?

The most common side effects of BiomePro are listed below. Tell your health care provider if you have any of these side effects that bother you.

  • Gas
  • Upset stomach

There may be other side effects of BiomePro that are not listed here. Contact your health care provider if you think you are having a side effect of a supplement. In the U.S., you can report side effects to the FDA at www.safetyreporting.hhs.gov or by calling 888-SAFEFOOD (888-723-3366). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of BiomePro?

While less common, the most serious side effects of BiomePro are described below, along with what to do if they happen.

Severe Allergic Reactions. BiomePro may cause allergic reactions, which can be serious. Stop taking BiomePro and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching or skin rash
  • Bumps on the skin called hives, which can be red, pink, white, or brown depending on your skin tone
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Serious Infections. In very rare cases, some people who take probiotics, such as BiomePro, can get a serious infection. This happens when the microbes move into a part of the body where they are not supposed to be, such as your blood. This is most likely to happen in people who are very sick or who have very weak immune systems, such as people with cancer or who are receiving chemotherapy. Call your health care provider right away if you have any of the following symptoms.

  • Fever, sweats, chills, or muscle aches
  • Tiredness
  • Shortness of breath
  • Fast heartbeat

Warnings & Precautions

Who should not use BiomePro?

Allergies to Ingredients. People who are allergic to any of the following should not take BiomePro.

  • Bifidobacteria
  • Lacticaseibacillus
  • Lactiplantibacillus 
  • Lactobacillus 
  • Any of the ingredients in the specific product

Your pharmacist can tell you all of the ingredients in BiomePro.

What should I know about BiomePro before using it?

BiomePro is a dietary supplement. It cannot be marketed to treat or cure a disease.

Read and follow the directions on the specific product you are taking, or take it as recommended by your health care provider.

Keep BiomePro out of the reach of children.

Premature infants can be at greater risk of side effects from probiotics, such as BiomePro. Talk to your health care provider about the risks if your infant was born prematurely.

The probiotics in BiomePro are measured in colony forming units (CFUs). Each CFU is equal to one living bacteria. The number of CFUs listed on the product label tells you how many living bacteria should be in that product on the day that it expires. Since bacteria slowly die off over time, the number of living bacteria in the product may be higher than the amount on the label.

Some probiotic products have been found to contain other microbes that are not listed on the label and that may cause serious health problems. The FDA has not tested BiomePro products to confirm that they contain the ingredients stated on their labels. Some dietary supplements have been tested by third-party organizations to confirm that they contain the ingredients listed on their labels and do not contain any harmful chemicals. Learn more about how to choose a safe dietary supplement product here.

What should I tell my health care provider before using BiomePro?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if BiomePro is right for you.

In particular, make sure that you discuss any of the following.

Central Line or Port. A central venous catheter (central line) or port is a small tube placed into a vein that can be used to give medicines and fluids directly into the vein (intravenously, or IV). These tubes can become infected by microbes, including those found in BiomePro. If you have a central line or port, speak with your health care provider before taking BiomePro.

Other Current and Past Health Conditions. Tell your health care provider if you have any of the following.

Other Medicines and Supplements. BiomePro may interact with other medicines and supplements. Before taking BiomePro, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Pregnancy. It is not known if or how BiomePro could affect pregnancy or harm a fetus. Tell your health care provider if you are pregnant or plan to become pregnant.

Breastfeeding. It is not known if BiomePro passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed.

How can I get more information about BiomePro?

For more information about BiomePro, you can visit the supplement maker’s website at www.metagenics.com/en-us/product/ultraflora-biomepro-probiotic or call them at 800-692-9400.

Interactions

Does BiomePro interact with foods or drinks?

There are no known interactions between BiomePro and foods or drinks.

It is unknown if drinking alcohol will affect BiomePro.

Does BiomePro interact with medicines (drug interactions)?

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before taking BiomePro.

  • A medicine that suppresses the immune system
  • An antibiotic, which is used to treat certain bacterial infections
  • Chemotherapy, which is used to treat certain cancers

The interactions between BiomePro and medicines are not fully understood. As with most dietary supplements, the research on drug interactions with BiomePro is incomplete. Always check with your health care provider before taking BiomePro with any medicines.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much BiomePro?

If you or someone else has used too much BiomePro, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of BiomePro?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

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